Ordering compounded medications is easier than ever. Ordering your pet's prescription drugs from Wedgewood Pharmacy is safe, and convenient. With a prescription number, easily refill prescriptions and enroll in the AutoRefill Program. May Be Prescribed by Vets for: Idiopathic epilepsy, pain management, seizures due to neonatal hypoxia. Search for Available Dosage Forms. Gabapentin is an anticonvulsant prescribed by veterinarians predominantly to treat chronic pain in dogs, cats, and other animals.
It also is used as a seizure-control agent, either by itself or in conjunction with other anti-seizure medications. Dosage can vary widely. Gabapentin is a structural analogue of GABA, an inhibitory neurotransmitter. Gabapentin is used in human medicine to treat seizures and many types of pain, including neuropathic pain, diabetic neuropathy, malignant pain, central pain, complex regional pain, and trigeminal neuralgia.
Gabapentin is used in both dogs and cats to treat chronic pain, particularly of neuropathic origin. It appears to be most effective when combined with other types of analgesic agents, for example NSAIDs, allowing prescribing lower doses. It has been shown to be an appropriate treatment for reducing hyperalgesia and allodynia associated with neuropathic pain.
It also is used in chronic arthritic pain and pain associated with malignancy. Gabapentin is used as an adjunctive therapy for dogs and cats with refractory idiopathic epilepsy. Clin Ther. Rational dosing of gabapentin and pregabalin in chronic kidney disease.
J Pain Rese. Oneschuk D, al-Shahri MZ. The pattern of gabapentin use in a tertiary palliative care unit. J Palliat Care. Real-world treatment of post-herpetic neuralgia with gabapentin or pregabalin. Clin Drug Investig. A two-year retrospective study of neuropathic pain management with gabapentin or pregabalin—Are we optimizing use in clinical practice? September 8, Patel R, Dickenson AH.
Mechanisms of the gabapentinoids and alpha 2 delta-1 calcium channel subunit in neuropathic pain. Pharmacol Res Perspect. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.
When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur.
Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:. Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
To do so may increase the chance of side effects. This medicine comes with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.
For patients with epilepsy who take gabapentin three times per day, do not allow more than 12 hours to pass between any 2 doses. The medicine works best if a constant amount is in the blood. Do not use the half-tablet if the whole tablet has been cut or broken after 28 days. Ask your doctor or pharmacist if you have any questions. Measure the oral liquid using a marked measuring spoon, oral syringe, or medicine cup.
The average household teaspoon may not hold the right amount of liquid. If you take an antacid that contains aluminum or magnesium, wait at least 2 hours before taking gabapentin. Only use the brand of this medicine that your doctor prescribed.
Evidence for other types of neuropathic pain is very limited. Around 3 or 4 out of 10 participants achieved this degree of pain relief with gabapentin, compared with 1 or 2 out of 10 for placebo. Over half of those treated with gabapentin will not have worthwhile pain relief but may experience adverse events. Conclusions have not changed since the previous update of this review. Gabapentin is commonly used to treat neuropathic pain pain due to nerve damage.
This review updates a review published in , and previous reviews published in , and To assess the analgesic efficacy and adverse effects of gabapentin in chronic neuropathic pain in adults. We also searched the reference lists of retrieved studies and reviews, and online clinical trials registries.
We included randomised, double-blind trials of two weeks' duration or longer, comparing gabapentin any route of administration with placebo or another active treatment for neuropathic pain, with participant-reported pain assessment. Two review authors independently extracted data and assessed trial quality and potential bias. We performed a pooled analysis for any substantial or moderate benefit.
Where pooled analysis was possible, we used dichotomous data to calculate risk ratio RR and number needed to treat for an additional beneficial outcome NNT or harmful outcome NNH. We included four new studies participants , and excluded three previously included studies participants. In all, 37 studies provided information on participants. Most studies used oral gabapentin or gabapentin encarbil at doses of mg or more daily in different neuropathic pain conditions, predominantly postherpetic neuralgia and painful diabetic neuropathy.
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